| | Leader | Born | Died | Nickname | Image |
| Henry Clay | 1777 | 1852 | Great Pacificator | Pushed the Missouri Compromise (1820 through the House | .. |
| John C. Calhoun | 1782 | 1850 | .. | the great defender of the agrarian South against the industrial North | .. |
| Daniel Webster | 1782 | 1852 | .. | placed the union above all other issues | webster.jpg |
| Thaddeus Stevens | 1792 | 1868 | .. | Representative from PA; impeachment leader | civil191.jpg |
| James M. Mason | 1798 | 1871 | .. | Envoy to England | civil154.jpg |
| Simon Cameron | 1799 | 1889 | .. | Lincoln's first Secretary of War | cameron.jpg |
| Millard Fillmore | 1800 | 1874 | .. | 13th president of the U.S | .. |
| David Farragut | 1801 | 1870 | Damn the torpedoes full speed ahead! | Admiral | farragut.jpg |
| Albert Sidney Johnston | 1803 | 1862 | .. | Confederate commander in the West | .. |
| William Lloyd Garrison | 1805 | 1879 | .. | founded the Liberator in 1831 and for 35 years campaigned for immediate and complete abolition of slavery. | CIVIL131.JPG |
| Robert Anderson | 1805 | 1871 | .. | Defender of Ft. Sumter | civil160.jpg |
| Stand Watie | 1806 | 1871 | .. | Cherokee; Last CSA general to surrender to the Union | .. |
| J. B. Magruder | 1807 | 1871 | Prince John | .. | .. |
| Joseph Eggleston Johnston | 1807 | 1891 | .. | Given command in the West | civil144.jpg |
| Robert E. Lee | 1807 | 1870 | King of Spades | Master strategist | lee.jpg |
| Jefferson Davis | 1808 | 1889 | .. | President of the Confederacy | civil151.jpg |
| Andrew Johnson | 1808 | 1875 | .. | Vice president | civil187.jpg |
| Salmon P. Chase | 1808 | 1873 | .. | Secretary of the Treasury; Chief Justice | chase.jpg |
| Abraham Lincoln | 1809 | 1865 | With malice towards none | Union President | civil188.jpg |
| Judah P. Benjamin | 1811 | 1884 | .. | Secretary of State | civil150.jpg |
| Horace Greeley | 1811 | 1872 | .. | Abolitionist | CIVIL132.JPG |
| Charles Sumner | 1811 | 1874 | .. | Senator from MA | civil192.jpg |
| Harriet Beecher Stowe | 1811 | 1896 | .. | author of Uncle Tom's Cabin | CIVIL136.JPG |
| John C. Fremont | 1813 | 1880 | Pathfinder of the West | .. | |
| Stephen A. Douglas | 1813 | 1861 | Little Giant | Defeated Lincoln in Senate election | civil186.jpg |
| Stephen Mallory | 1813 | 1873 | .. | .. | mallory.jpg |
| Philip Kearny | 1814 | 1862 | .. | .. | .. |
| Joseph Hooker | 1814 | 1879 | Fightin Joe | Hero at Antietam; scapegoat at Chancellorsville | hooker.jpg |
| William J. Hardee | 1815 | 1873 | Old Reliable | .. | .. |
| George Gordon Meade | 1815 | 1872 | .. | Won the battle of Gettysburg | civil170.jpg |
| Henry W. Halleck | 1815 | 1872 | Old Brains | .. | halleck.jpg |
| James A. Seddon | 1815 | 1880 | .. | Secretary of War | civil155.jpg |
| Nathaniel P. Banks | 1816 | 1894 | .. | .. | banks.jpg |
| George Henry Thomas | 1816 | 1870 | Rock of Chickamagua | In 1864 he defeated Gen. Hood in the battle of Nashville. | civil177.jpg |
| Frederick Douglass | 1817 | 1895 | | Abolitionist; escaped from slavery to become anti-slavery editor and leader | CIVIL130.JPG |
| Edward R.S. Canby | 1817 | 1873 | .. | Commander Dept of NM; later captured Mobile in 1865 | .. |
| Braxton Bragg | 1817 | 1876 | .. | Unsuccessfully tried to invade KY with Army of Tennessee | bragg.jpg |
| Wade Hampton | 1818 | 1902 | .. | .. | .. |
| Nathaniel Lyon | 1818 | 1861 | .. | One of the most promising Union officers | .. |
| Benjamin F. Butler | 1818 | 1893 | Beast | .. | civil162.jpg |
| Don Carlos Buell | 1818 | 1898 | .. | .. | buell.jpg |
| Pierre G. T. Beauregard | 1818 | 1893 | .. | After directing the bombardment of Fort Sumter | CIVIL138.JPG |
| Walt Whitman | 1819 | 1892 | .. | poet | CIVIL137.JPG |
| William S. Rosecrans | 1819 | 1898 | .. | .. | .. |
| William Tecumseh Sherman | 1820 | 1891 | War is hell! | Led the Army of the West thru the Carolinas | civil176.jpg |
| David Harvey Hill | 1821 | 1889 | .. | .. | .. |
| John C. Breckinridge | 1821 | 1875 | .. | Democratic Presidential nominee | civil139.jpg |
| Clara Barton | 1821 | 1912 | .. | Founded American Red Cross | civil194.jpg |
| James Longstreet | 1821 | 1904 | .. | His delay in taking the offensive at Gettysburg may have cost Gen. R.E. Lee the battle. | civil146.jpg |
| Ulysses S. Grant | 1822 | 1885 | Unconditional Surrender | Captured Vicksburg | Grant.jpg |